Clinical Trials & Research

Healthy skin is determined by a complex arrangement and interaction of a number of factors. This case study presents a clinical trial that aimed to evaluate an oral supplement’s effect on some of these skin dimensions. Challenges and objectives The experience that the Atlantia team offered when designing and performing skin studies to support a

In a study published in the journal Bioengineered, a team of researchers used bioinformatics tools to explore the biological characteristics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected myocardium. Study: Inflammatory activation and immune cell infiltration are main biological characteristics of SARS-CoV-2 infected myocardium. Image Credit: Kateryna Kon/Shutterstock SARS-CoV-2 directly invades the human heart by targeting

1. International Diabetes Federation. IDF Diabetes Atlas, 9th edn. Brussels, Belgium. 2019. http://www.idf.org/sites/default/files/Atlas-poster-2014_ES.pdf. 2. Riaz H, Khan MS, Siddiqi TJ, Usman MS, Shah N, Goyal A, et al. Association between obesity and cardiovascular outcomes: a systematic review and meta-analysis of Mendelian randomization studies. JAMA Netw Open. 2018;1:e183788. PubMed  PubMed Central  Google Scholar  3. Tuomilehto J,

In a recent study posted to the medRxiv* pre-print server, a team of researchers estimated the probability of undetected emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant in 25 low and middle-income countries (LMICs) by early December. Study: The risk of SARS-CoV-2 Omicron variant emergence in low and middle-income countries (LMICs).

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In a recent study posted to the medRxiv* pre-print server, a team of researchers conducted a case-control study at a mass vaccination center in Japan to evaluate acute and long-term adverse events following immunization (AEFI) with coronavirus disease 2019 (COVID-19) Moderna vaccine. Study: Incidence and Risk Factors of Immediate Hypersensitivity Reactions and Immunisation Stress-related Responses

1. Correll CU, Solmi M, Veronese N, Bortolato B, Rosson S, Santonastaso P, et al. Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: a large-scale meta-analysis of 3,211,768 patients and 113,383,368 controls. World Psychiatry. 2017;16:163–80. Article  Google Scholar  2. Olfson M, Gerhard T, Huang C, Crystal S,

As my kindergartner fumbled with his shoes, I stood at our door sifting through the mental parenting checklist newly lodged in my brain: backpack. Sweatshirt. Snacks. Sunscreen. Water bottle. KN95 mask. Vaccination card. Jesse asked for his cloth mask, and I explained again that if he wore that one he’d need to have on a

1. Rezaei S, Abdurahman AA, Saghazadeh A, Badv RS, Mahmoudi M. Short-term and long-term efficacy of classical ketogenic diet and modified Atkins diet in children and adolescents with epilepsy: a systematic review and meta-analysis. Nutr Neurosci. 2019;22:317–34. CAS  PubMed  Google Scholar  2. Sourbron J, Klinkenberg S, Kuijk SMJV, Lagae L, Majoie M. Ketogenic diet for

Since December 2019, Wuhan, China, has been conducting influenza and related disease monitoring, and a number of cases of viral pneumonia have been discovered, all of which have been diagnosed as viral pneumonia or pulmonary infection. The World Health Organization (WHO) designated it a novel coronavirus (2019-nCoV) on January 12, 2020. The coronavirus Research Group dubbed

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Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has been causing coronavirus disease (COVID-19), a pandemic that has been ruling our lives ever since early 2020.  The virus is a member of the coronavirus family, seven out of which (NL63, 229E, HKU1, OC43, SARS, MERS and SARS-CoV-2) are known to infect humans and all of these

Most patients who undergo curative-intent resection for pancreatic cancer are malnourished. This correlates with poor outcomes. There are no guidelines for the nutritional management of these patients. We aimed to establish current UK practice by surveying all hepatopancreatobiliary (HPB) units. Questions covered: dietetic service, nutrition risk screening (RS), micronutrients, prehabilitation, nutritional support, pancreatic exocrine replacement

The coronavirus disease 2019 (COVID-19) pandemic has been ongoing for over two years now, and lack of compliance, vaccine hesitancy, and apparent apathy have grown over time. This has reached the point where some public figures have openly argued for the reduction of non-pharmaceutical interventions, even in cases where this would increase disease incidence. In

1. Mave V, Erlandson KM, Gupte N, Balagopal A, Asmuth DM, Campbell TB, et al. Inflammation and change in body weight with antiretroviral therapy initiation in a multinational cohort of HIV-infected adults. J Infect Dis. 2016;214:65–72. CAS  Article  Google Scholar  2. Duggal S, Chugh TD, Duggal AK. HIV and malnutrition: Effects on immune system. Clin

From Ziath LtdJan 12 2022Reviewed by Maria Osipova Ziath announce the Uno single tube reader – a powerful device packed with exciting features to make your sample management work with 2D barcoded tubes easier and faster. Uno single tube reader. Image Credit: Ziath Ltd. Measuring just 66 x 53.5 x 51.5 millimetres – the rugged

In a recently published study on the medRxiv* pre-print server, a team of researchers analyzed differential protein glyco-isoform distributions of symptomatic and asymptomatic coronavirus disease 2019 (COVID-19) patients.  Study: Differential Peripheral Blood Glycoprotein Profiles in Symptomatic and Asymptomatic COVID-19. Image Credit: Corona Borealis Studio/Shutterstock Several biomarkers, including interleukin 6 (IL-6) and C-reactive protein (CRP), have

Since coronavirus disease 2019 (COVID-19) first emerged, vast strides have been made in detection and testing technology. During the initial phases of the pandemic, while countries were forced to rely on ad-hoc PCR assays to confirm infection with the disease, most governments told anyone showing symptoms to isolate. Study: Nanobody-Functionalized Cellulose for Capturing SARS-CoV-2. Image

How can we shift from a state of inattentiveness to one of highest attention? The locus coeruleus, literally the “blue spot,” is a tiny cluster of cells at the base of the brain. As the main source of the neurotransmitter noradrenaline, it helps us control our attentional focus. Synthesizing evidence from animal and human studies,

Mechanical engineering and materials science professor David Needham has shown that a slight increase in solution pH might be all it takes to turn a metabolic inhibiting drug, traditionally used to treat gut parasites, into a promising prophylactic/preventative nasal spray and early treatment throat spray for COVID-19. The results appear online on December 28 in

1. Pirlich, M. & Lochs, H. Nutrition in the elderly. Best Pract. Res. Clin. Gastroenterol. 15, 869–884 (2001). CAS  PubMed  Google Scholar  2. Keller, H. H., Østbye, T. & Goy, R. Nutritional risk predicts quality of life in elderly community-living Canadians. J. Gerontol.: Ser. A 59, M68–M74 (2004). Google Scholar  3. Goates, S., Du, K.,

Sponsored Content by Ziath LtdJan 4 2022Reviewed by Maria Osipova Data produced by the State of California shows one of its main test suppliers, SummerBio LLC, based in Menlo Park, California, has delivered millions of tests for the Los Angeles and Santa Monica Unified School districts at the cost of just $10 each. Image Credit: