Wound Care

Orthopaedics faculty at LSU Health New Orleans participated in a study comparing two antisepsis aqueous solutions in reducing the risk of infection in patients requiring surgery for open fractures. In the largest known randomized-controlled trial, the research team found that contrary to current international recommendations, chlorhexidine gluconate was not superior to povidone-iodine in an alcohol

Every year around 2 million people die worldwide from hemorrhaging or blood loss. Uncontrolled hemorrhaging accounts for more than 30% of trauma deaths. To stop the bleeding, doctors often apply pressure to the wound and seal the site with medical glue. But what happens when applying pressure is difficult or could make things worse? Or

Even months after critical illness for sepsis, children are at risk for new or worsening medical conditions, a study suggests. One in five children in a national cohort either developed or experienced progressing disease within six months of leaving the intensive care unit for sepsis, according to the research in JAMA Pediatrics. Researchers compared data

From LabskinSep 27 2022Reviewed by Maria Osipova Labskin and University of Bradford team up to bring new science in skin health to greater diversity for skin types. Pictured below from left to right: Dr Sobia Kauser, Assistant Professor University of Bradford, Dr. David Caballero-Lima, Chief Scientist Labskin, Dr. Jacobo Elies Gomez, Assistant Professor, University of

A University of Cincinnati study found administering an immunotherapy drug before surgery for oral cavity cancer did not lead to increased rates of complications during and after surgery. The findings were published Aug. 25 in the journal JAMA Otolaryngology — Head & Neck Surgery. Alice Tang, MD, first author on the study, said the research

The study, which includes the first resource detailing the role of microRNAs in the wound-repair process, shows that aberrant levels of a trio of microRNAs may impair healing in venous ulcers. The findings suggest that drugs targeting these microRNAs could help facilitate healing in patients. Venous ulcers commonly occur in the legs, caused by poor

A new clinical-grade collagen made from discarded bullfrog skin is leapfrogging from the lab bench to clinics soon. The collagen is developed by materials scientists from Nanyang Technological University, Singapore (NTU Singapore) in collaboration with Singapore medical technology firm Cuprina Wound Care Solutions (Cuprina), which specializes in developing products that treat chronic wounds, such as

A single chemical is key to controlling when hair follicle cells divide, and when they die. This discovery could not only treat baldness, but ultimately speed wound healing because follicles are a source of stem cells. Most cells in the human body have a specific form and function determined during embryonic development that does not

The American Society of Colon and Rectal Surgeons has issued updated guidelines for physicians, published in Diseases of the Colon & Rectum, about how to treat problems of the anus and rectum called anorectal abscess, anal fistula, and rectovaginal fistula. The journal is published in the Lippincott portfolio by Wolters Kluwer. The guidelines were prepared

The Indiana Center for Regenerative Medicine and Engineering (ICRME) at Indiana University School of Medicine is home to tissue nanotransfection (TNT) regenerative medicine technology that achieves functional tissue reprogramming in the live body. Last year, ICRME researchers published on how to manufacture the TNT 2.0 silicon chip hardware in Nature Protocol. Now, their research demonstrates

The Indiana Center for Regenerative Medicine and Engineering (ICRME) at Indiana University School of Medicine is home to tissue nanotransfection (TNT) regenerative medicine technology that achieves functional tissue reprogramming in the live body. Last year, ICRME researchers published on how to manufacture the TNT 2.0 silicon chip hardware in Nature Protocol. Now, their research demonstrates

Antibiotic resistant bacterial pathogens are increasingly playing a role in rising illness and preventing wound healing, especially in hospitals. While more and more pathogens have developed biofilms that protect them from being eradicated by antibiotics, fewer classes of antibiotics are being developed. Researchers from Ben-Gurion University of the Negev decided to go in a different

One of the biggest concerns for patients undergoing skin grafting is scarring post-surgery and the regeneration of transplanted skin. The depth of scarring after suturing varies depending on the skill of the medical personnel performing the skin grafting, and wound healing at the suture site requires over a month. Recently, a Korean research team has

Robot-assisted surgery used to perform bladder cancer removal and reconstruction enables patients to recover far more quickly and spend significantly (20 per cent) less time in hospital, concludes a first-of-its kind clinical trial led by scientists at UCL and the University of Sheffield. The study, published in JAMA and funded by The Urology Foundation with

Tissues often fail to regenerate from traumatic muscle-loss injuries such as gunshot wounds and car accidents, and new research in mice from the University of Michigan sheds light on why. The findings suggest new treatment strategies that could eventually restore function and prevent limb loss. Skeletal muscle is the tissue that defines how we move

Patients kept at a body temperature of 37 C during major surgery had no fewer cardiac complications than patients kept at 35.5 C, according to data presented at the American College of Cardiology’s 71st Annual Scientific Session. There were also no differences in the number of infections or required blood transfusions in patients kept at

Treating wounds with an extract taken from wild blueberries may improve healing, according to a new study. The research will be presented this week in Philadelphia at the American Physiological Society’s (APS) annual meeting at Experimental Biology 2022. More than $50 billion is spent on wound care each year. Chronic wounds, such as diabetes-related sores

Patients who undergo facial surgery think their surgical scars look worse than surgeons and independent observers do, according to a new study from the Perelman School of Medicine at the University of Pennsylvania. Surgeons and those not tied personally to the particular scarring felt similarly about how significant a scar appeared, but those who looked

Research carried out by RCSI University of Medicine and Health Sciences has revealed new information about how blood clots are formed during wound healing. The research, published tomorrow in Science Advances, examines the behaviour of platelets at a wound site, specifically their ability to sense where within a blood clot they are and remodel their

A team led by Maria Leptin has shown in the fruit fly Drosophila that autophagy, a mechanism of stress responses in cells, plays an important role in wound healing: When a wound heals, the process of autophagy is initiated and regulated by the protein complex TORC1. This is a newly discovered function of autophagy and

Results from an international, randomized, double-blind, placebo-controlled, phase 3 clinical trial indicate that adding the androgen-receptor inhibitor darolutamide to androgen-deprivation therapy and chemotherapy prolongs the survival of men with metastatic, hormone-sensitive prostate cancer, a disease that is fatal in most cases. The study, which was conducted by a team led by investigators at Massachusetts General

New research led by the University of Bristol has found the protein p53 plays a key role in epithelial migration and tissue repair. The findings could improve our understanding of the processes used by cells to repair tissues, and be used to identify interventions that could accelerate and improve wound repair. Epithelial tissues are the