No one studying polio knew more than Albert Sabin, the Polish-American scientist whose vaccine against the crippling disease has been used worldwide since 1959. Sabin’s oral vaccine provides lifelong immunity. It has one drawback, which Sabin, who died in 1993, fiercely disputed: In rare cases, the weakened live poliovirus in the vaccine can mutate, regain
Children
New research has advanced COVID-19 vaccine work in several ways: using a modified live attenuated mumps virus for delivery, showing that a more stable coronavirus spike protein stimulates a stronger immune response, and suggesting a dose up the nose has an advantage over a shot. Based on these combined findings in rodent experiments, Ohio State
While infants exposed to opioids during their mother’s pregnancy have been linked to adverse health outcomes, a new study at the University of Missouri has found prenatal opioid exposure could trigger long-term neurological or behavioral effects later in a child’s life. The key is the opioid’s impact on the developing fetus’ gut microbiome – a
JMIR Publications recently published “Web-Based Training for Nurses on Using a Decision Aid to Support Shared Decision-making About Prenatal Screening: Parallel Controlled Trial” in JMIR Nursing which reported that in this study, these authors aimed to assess the impact of a shared decision-making (SDM) training program on nurses’ intention to use a decision aid with
Elementary school-age children who get less than nine hours of sleep per night have significant differences in certain brain regions responsible for memory, intelligence and well-being compared to those who get the recommended nine to 12 hours of sleep per night, according to a new study led by University of Maryland School of Medicine (UMSOM)
Despite a federal mandate requiring access to early intervention programs (EIP) for children with disabilities, fewer than half of autistic children in four New Jersey counties received services before 36 months of age, according to a Rutgers study. Income and race-based disparities were significant obstacles to accessing EIP support, researchers found. “For infants and toddlers
Side effects from pediatric drug treatment are responsible for nearly 10 percent of childhood hospitalizations, with nearly half of those being life-threatening. Despite the need to know more about these drugs and the adverse events they can have on children, little evidence is currently available. Clinical trials remain the gold standard for identifying adverse drug
Infants from minoritized racial and ethnic backgrounds who have positive newborn screening tests for cystic fibrosis received their diagnostic follow-up for the disease later than recommended and later than white, non-Hispanic infants, according to a study published in the Journal of Cystic Fibrosis. The study also found that this delay in diagnosis and treatment was
What do building pyramids, going to the moon, paddling a two-person canoe or dancing a waltz have in common? All these actions are the result of a common goal between multiple partners and lead to a mutual sense of obligation, known as “joint commitment”. This ability to cooperate is universal in humans and to certain
One in two premature babies receives transfusions of red blood cells (RBC) due to anemia. There are no generally accepted clinical guidelines for the degree of anemia necessitating blood transfusions. MedUni Vienna researchers have now conducted a critical review of the currently available literature. Their review has been published in the prestigious journal “The Lancet
Ofsted has today published a report on the ongoing impact of the Covid-19 pandemic on children’s social care, drawing on evidence from inspections, focus groups and interviews with inspectors. Read ‘Children’s social care 2022: recovering from the COVID-19 pandemic’. The report finds that the pandemic has exacerbated long-standing staffing challenges in children’s social care, which
Attending daycare in the first three years of life is linked with an increase in lung complications in children who were born prematurely and diagnosed with a form of chronic lung disease, according to new research led by Children’s Hospital of Philadelphia (CHOP). The multicenter study, which drew data from nine specialty centers across the
In a 2021 media statement released by the United States Centers for Disease Control and Prevention (CDC), the agency provided a series of updated guidelines on how the U.S. population can protect themselves and others from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC). Six months later, these guidelines still
While most people recover from COVID-19 within a week or two, up to one-third of survivors experience persistent or new symptoms weeks and months after initial infection. One form of “long COVID” is interstitial lung disease (ILD), a group of chronic pulmonary disorders characterized by inflammation and scarring (fibrosis) that make it hard for the
Young women and girls’ time spent in unpaid household work contributes to the gender pay gap, according to new research from the Universities of East Anglia (UEA), Birmingham and Brunel. The research shows women’s later employment participation is affected by taking on the weight of this care burden in childhood, thus adding to existing inequality
A Rutgers researcher was part of a National Institutes of Health study that found pregnant women who were exposed to chemical compounds known as phthalates during pregnancy had an increased risk of preterm birth. Phthalates are industrial chemicals used in personal-care products, such as cosmetics, as well as solvents, detergents and in food packaging. After
The annual death rate of children under five years old could double to about 38,000 by 2049 compared with the decade 2005-2014, without cuts to rising carbon emissions, a study estimates. The study published in Environmental Research Letters this month (4 July) predicts that keeping temperature rise at 1.5 degrees Celsius through to 2050 as
We often hear the phrase ‘growing pains’ used by the general public to describe muscle or joint pain in young people and the term is also used by health professionals. However researchers have found there is no consistent medical definition of the condition behind a diagnosis. A broad review of medical literature by University of
Nearly 6 percent of children who presented to the Emergency Department (ED) with COVID-19 reported symptoms of long COVID 90 days later, according to a study conducted in eight countries and published in JAMA Network Open. Initial hospitalization of 48 or more hours, four or more symptoms at the initial ED visit, and age 14
Antibodies that summon virus-engulfing white blood cells may play an important role in protecting infants from potentially serious congenital infection with human cytomegalovirus (HCMV), according to a study led by an investigator at Weill Cornell Medicine and NewYork-Presbyterian. The study, which appeared June 28 in the Journal of Clinical Investigation, was the most comprehensive analysis
The transition to kindergarten is a notable milestone for children and families, who typically prepare by gathering school supplies and meeting the teacher. New research suggests that one important way to prepare for the transition to first-time schooling is to develop a bedtime routine in which children consistently get at least 10 hours of sleep
The Focused Ultrasound Foundation and the Children’s Tumor Foundation (CTF) have established a partnership to advance innovative, noninvasive treatments in pediatrics. For more than 15 years, the Focused Ultrasound Foundation has been dedicated to advancing the development and adoption of focused ultrasound. Likewise, for over 40 years, CTF has been a leader in driving research,
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