Clinical Trials & Research

Frozen shoulder, or adhesive capsulitis, is a common cause of shoulder pain and immobility. New findings point to specific genes associated with an increased risk of this condition, reports The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer. The risk genes are associated with

In a recent study posted to the bioRxiv* preprint server, researchers investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein activity in terms of calcium cations (Ca2+) cations. Study: The SARS-CoV-2 envelope (E) protein forms a calcium- and voltage-activated calcium channel. Image Credit: PHOTOCREO Michal Bednarek/Shutterstock Functional ion channels are critical in the

The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in 2019 in Wuhan, China. The subsequent global transmission of SARS-CoV-2 ultimately led to the coronavirus disease 2019 (COVID-19) pandemic. Implementing strict prevention measures and quarantine policies rapidly decreased COVID-19 cases in China. Despite these efforts, several localized COVID-19 outbreaks have

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In a recent study posted to the bioRxiv* preprint server, researchers investigated the expression of complement regulatory proteins (CRPs) in coronavirus disease 2019 (COVID-19) to identify potential dysregulated CRP patterns and investigate whether they contribute to COVID-19 pathogenesis. Study: Upregulation of CD55 complement regulator in distinct PBMC subpopulations of COVID-19 patients is associated with suppression

Persons living with diabetes are at greater risk of a number of health conditions including eye and foot problems, heart attacks and strokes, and kidney and nerve damage. A new study suggests that the earlier a woman becomes diabetic, the earlier she will likely enter menopause. Study results will be presented during The North American

Database In order to develop an AI system that successfully identifies food groups based on food images taken in everyday scenarios, we require a large number of appropriately annotated data. We created such a dataset, consisting of images that were captured under free-living conditions. A group of expert academic dietitians identified 31 categories of food

Community diagnostic centers (CDCs) have delivered more than two million vital tests, checks and scans for patients, with a further 10 centers now approved, the Health and Social Care Secretary has announced today October 11. These centers are busting the Covid backlogs by speeding up access to lifesaving tests. The one-stop shops, backed by £2.3

In a recent study posted to the medRxiv* preprint server, researchers estimated the association of first-generation messenger ribonucleic acid (mRNA) vaccines (BNT162b2, mRNA-1273) with coronavirus disease 2019 (COVID-19)-related medical encounters. Study: Association between COVID-19 mRNA vaccination and COVID-19 illness and severity during Omicron BA.4 and BA.5 sublineage periods. Image Credit: CKA/Shutterstock Related Stories The researchers

When struggling to conceive, every second that ticks by feels precious. That makes it easy to get discouraged: 65 percent of those who seek fertility care eventually discontinue treatment, the majority due to stress. That’s why Penn Medicine recently instituted a telemedicine-driven program aimed at seeing patients more quickly and starting treatments sooner. The program,

Amid much speculation and research about how our genetics affect the way we age, a University of California, Berkeley, study now shows that individual differences in our DNA matter less as we get older and become prone to diseases of aging, such as diabetes and cancer. In a study of the relative effects of genetics,

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A team of researchers at Northwestern University has devised a new platform for gene editing that could inform the future application of a near-limitless library of CRISPR-based therapeutics. Using chemical design and synthesis, the team brought together the Nobel-prize winning technology with therapeutic technology born in their own lab to overcome a critical limitation of

Researchers at Delft University of Technology, VU University Amsterdam and Radboud University in the Netherlands developed a new technique for monitoring biological rates in dynamic microbial systems using on-line measurements from a Thermo Scientific Prima BT benchtop mass spectrometer.1 Image credit: Shutterstock/ymd2881 Making sense of microbial worlds Microbial communities are complex, dynamic systems in which

Alzheimer‘s disease (AD) is the most common type of neurodegenerative disease and dementia and has posed a significant global health challenge in aging sections of society. There are several treatments available for Alzheimer’s disease; however, these only provide temporary symptomatic improvements.  Cannabis sativa L. has been recognized for thousands of years due to its psychoactive

In this study, prior to hyperbaric therapy, a number of negative differences in the perception of the five basic tastes were demonstrated by type II diabetes with diabetic foot ulcers when compared to the controls. These concerned the recognition threshold for basic tastes and the intensity of taste sensation of suprathreshold concentrations. Differences were also

Making sense of the complex metabolic activity of microbial communities is no mean feat. Understanding the stoichiometry and reaction kinetics of this activity typically requires precise quantification of reactants, metabolic products, and the composition of the microbial community itself. Researchers at the universities of Delft and Wageningen in the Netherlands used mass spectrometry, gas chromatography

High-quality parenting practices in adolescence lay the foundation for close parent-child relationships when the children become young adults, according to new research from Penn State. The study is one of the first to examine how changes in parental involvement, parental warmth, and effective discipline during adolescence predict the quality of the relationships between parents and

Researchers in the United States published a study in the journal PLOS Pathogens that examined the shedding of infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virions despite vaccination against it. Study: Shedding of infectious SARS-CoV-2 despite vaccination. Image Credit: MrSquid / Shutterstock Background The SARS-CoV-2 Delta variant was first identified in March 2021 and was linked

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Sweden’s Reproduction Medicine Center (RMC) in Malmo is one of Sweden’s largest public reproductive healthcare facilities. In recent years, a major expansion of the clinic’s services has created an essential need to expand the premises and introduce new state-of-the-art equipment. Following many years of careful development and planning, the new center was opened in October

It is estimated that around 10% of the US population has peanut allergies, a medical emergency that can be treated but not cured. Compared to those without allergies, these individuals are at a greater risk of anaphylaxis. Hence, there is a need to develop novel therapies to treat peanut and other food allergies. A recent Frontiers