Clinical Trials & Research

Reviewed by Emily Henderson, B.Sc.Sep 8 2020 The University of Texas MD Anderson Cancer Center and Astex Pharmaceuticals, Inc., a wholly owned subsidiary of Otsuka Pharmaceutical Co. Ltd., based in Tokyo, Japan, today announce a strategic collaboration agreement aimed at accelerating the clinical evaluation of Astex’s pipeline of products for patients with certain types of
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Print this page 19 August 2020 – GlaxoSmithKline plc (LSE/NYSE: GSK) today announced that patient dosing has begun in a phase III clinical programme investigating its 5-in-1 meningitis (MenABCWY) vaccine candidate compared to licensed meningococcal vaccines, Bexsero and Menveo. Emmanuel Hanon, Senior Vice President and Head of Vaccines R&D for GSK, said: “Entering the final stage of
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With the use of an accurate high throughput assay, researchers from the Weizmann Institute of Science and Magen David Adom Blood Services in Israel showed substantial inter-individual variability and antibody cross-reactivity against seasonal coronaviruses upon SARS-CoV-2 infection, with important implications for immune surveys and vaccines. The study is currently available on the medRxiv* preprint server.
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Print this page TARRYTOWN, N.Y., Aug. 19, 2020 /PRNewswire/ — Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that the New England Journal of Medicine (NEJM) published positive results from the Phase 3 trial of evinacumab in 65 patients with homozygous familial hypercholesterolemia (HoFH). Evinacumab is an investigational medicine that binds to and blocks the function of angiopoietin-like 3 (ANGPTL3), and is
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Reviewed by Emily Henderson, B.Sc.Sep 4 2020 In contrast to WHO´s and other expert´s advice, the worst-off countries should be extra prioritised when it comes to COVID-19 vaccine allocation, according to Professor Ole Frithjof Norheim at the University of Bergen. Once effective COVID-19 vaccines are approved, they will be scarce. WHO and others have promised
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Print this page CAMBRIDGE, Mass.–(BUSINESS WIRE)– September 2, 2020 — Amylyx Pharmaceuticals, Inc., a pharmaceutical company focused on developing new treatments for amyotrophic lateral sclerosis (ALS), Alzheimer’s disease and other neurodegenerative diseases, today announced the publication of results from the pivotal CENTAUR trial evaluating AMX0035 – an investigational neuroprotective therapy designed to reduce the death
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Reviewed by Emily Henderson, B.Sc.Sep 2 2020 Our gut microbiota can crucially influence our behavior and neurodevelopment. New research of the Ethology Department at the Faculty of Science at Eötvös Loránd University indicates that dogs’ aging mechanism and memory performance are also linked to their gut microbiome composition. According to the study, dogs and humans
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Print this page NEW YORK and MAINZ, Germany, Aug. 20, 2020 (GLOBE NEWSWIRE) —  Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) today shared additional Phase 1 safety and immunogenicity data from their ongoing U.S. study of the BNT162 mRNA-based vaccine program against SARS-CoV-2, which has advanced into Phase 2/3 evaluation. The newly released manuscript describes key
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