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Britain will offer additional COVID-19 shots to participants in clinical trials for coronavirus vaccines that have not yet been approved in order to let them travel, the health ministry said on Friday. People enrolled in trials for shots made by the likes of Novavax and Valneva have been in limbo, as the shots have not been approved,

Early in the pandemic, scientists thought “convalescent plasma” might be a way to treat COVID-19. By giving patients the plasma of people who had recovered (or convalesced) from COVID-19, the idea was this antibody-rich infusion would help their immune systems fight infection. It’s a strategy tried, with various degrees of success, for other infectious diseases,

Pfizer asked the U.S. government Thursday to allow the use of its COVID-19 vaccine in children ages five to 11 — and if regulators agree, shots could begin within a matter of weeks. The move comes as the pharmaceutical giant is also planning to formally file for authorization of the shot in Canada in mid-October, as

The shift from medical school to residency has long pushed young doctors to their physical and mental limits. A new comprehensive report proposes a slate of reforms to make the path smoother and give doctors-in-training a stronger foundation to guide them through years of practice. The report, drafted by the Coalition for Physician Accountability’s Undergraduate

The combination of doxorubicin and trabectedin (Yondelis) continued to show encouraging activity as first-line treatment of patients with metastatic or unresectable leiomyosarcoma (LMS), according to results from the phase III LMS-04 trial presented at the recent European Society for Medical Oncology (ESMO) virtual meeting. In this exclusive MedPage Today video, Mark Agulnik, MD, sarcoma section

A number of late-phase studies in colorectal cancer have opened in recent months. Could one of your patients benefit from being enrolled? Metastatic colorectal cancer. Patients with colorectal cancer whose condition has progressed with or has demonstrated intolerance to first-line therapy for metastatic disease are sought for a trial of the use of a circulating-tumor

If you’re a K-pop fan, then you know how their beaming smiles can easily brighten up anyone’s day. It’s an important part of a K-pop idol’s look.  Here’s a look at the 10 best smiles in K-pop, which may inspire you to improve yours as well. Best Smiles in K-pop 1. Jisoo (Blackpink) Jisoo Photo by Stuart C.

Urgent action from all levels of government is needed to bring Canada’s strained health-care system “back to life” as the COVID-19 pandemic keeps raging, medical leaders warned in a Wednesday briefing. The remarks followed an emergency summit Tuesday night, which brought together more than 30 national and provincial health organizations including the Canadian Medical Association (CMA) and

For people with hypertension and left ventricular hypertrophy (LVH), getting their blood pressure down as low as possible could help reduce their risk for cardiovascular disease (CVD) events, new research suggests. In a nationwide cohort study of Korean adults with LVH who were followed for more than 11 years, patients with a systolic blood pressure

At the European Society for Medical Oncology (ESMO) virtual meeting, researchers presented the results of a study evaluating the combination of entinostat, nivolumab (Opdivo), and ipilimumab (Yervoy) in patients with advanced HER2-negative breast cancer. At the recommended phase II dose, this combined approach was associated with expected immune-related adverse events in advanced HER2-negative breast cancer.

The Centers for Disease Control and Prevention (CDC) released a holiday gathering guidance on its website only to remove it shortly after it caused confusion among medical experts and the general public who read it.  Controversy Over CDC’s Holiday Guidance As the holidays are fast approaching, the public health agency decided to issue a new guidance

Unless pneumonia is suspected, clinicians should not prescribe antibiotics for most children with chest infections, according to findings of the ARTIC-PC randomized controlled trial, published in The Lancet. “Prescribing for children with uncomplicated chest infections is still common in most countries,” said lead author Paul Little, MD, professor of primary care research at the University

A new study using Canadian data suggests the delta variant of the COVID-19 virus causes more serious disease and is associated with an increased risk of death compared to previous strains — dangers that are drastically reduced with vaccination. The study, conducted by researchers at the University of Toronto and published Tuesday in the Canadian

Medtronic has updated a previous recall of its MiniMed 600 series insulin pumps to include all with a potentially problematic clear retainer ring, not just those that appear damaged. The U.S. Food and Drug Administration announced on Oct. 5 that Medtronic will now replace any MiniMed 600 series pump that has a clear retainer ring with an

Greetings. I write briefly to inform you I am aware of your Google Review placed nearly a week ago. I’m not upset, but I must say that I am rather surprised by some of the statements. It is germane to the situation when a patient expresses displeasure about his or her experience with our office

Prurigo pigmentosa, an uncommon inflammatory skin condition also known as Nagashima disease, is growing in frequency, possibly as a result of increased interest in the ketogenic diet, according to a dermatologist, who reviewed skin conditions common to patients of Asian descent at the Skin of Color Update 2021. “Ketogenic diets are gaining popularity globally for

Jennifer Rosebluff-Thomas is being remembered by her sister as a beautiful, vibrant woman who lived for her children until she died of COVID-19 in an Edmonton ICU in early September. “Her kids — that was her world,” said her older sister, Carol Charles. “That’s what made her smile every day. That’s who she got up

Discovery of substantial atrial fibrillation (AF) is usually an indication to start oral anticoagulation (OAC) for stroke prevention, but it’s far from settled whether such AF is actually a direct cause of thromboembolic stroke. And that has implications for whether patients with occasional bouts of the arrhythmia need to be on continuous OAC.   It’s

A 60-year-old man presented to the hospital after being referred by his general practitioner. He explained on admission that he had been in good health until about 10 weeks earlier, when he began to have episodes of coughing and fever. Clinicians also noted blisters around his mouth extending to his nostrils. The patient said his

Meet people where they are. It’s a disruptive concept is taking hold in many areas of medicine, none so much as in the HIV/AIDs arena, where home-based self-testing finally appears to be gaining traction beyond the boundaries of clinical research and advocacy. HIV self-testing is not a new concept; data supporting efficacy and upticks in

Pfizer and its partner BioNTech have submitted preliminary data from their trial for a COVID-19 shot for kids to Health Canada earlier than expected, the department confirmed Saturday. A formal filing of the submission for authorization of a vaccine for children is expected in mid-October, according to an email from Health Canada. Authorization of a vaccine for

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. COVID-19 deaths are beginning to plateau in the US, adding another promising sign that the latest coronavirus surge has peaked. The 7-day average of daily deaths has hovered around 2000 for more than a week and dropped below 1900 on Thursday.