Calanus oil may improve glucose and insulin measures in obese people: RCT

Nutrition & Life

Writing in Nutrients​, scientists from Leibniz University Hannover and Hannover Medical School report that 12 weeks of calanus oil supplements led to significant reductions in fasting plasma insulin and HOMA-IR in obese people.

Significant improvements in hepatic insulin resistance index (HIRI) were also reported from Calanus oil supplementation, but no impacts were seen on other measures, such as HbA1c.

“Our results indicate that Calanus oil causes beneficial effects on glucose metabolism and insulin resistance in obese patients, with clinical relevance to be verified in further studies,” ​wrote the scientists.

Sourced from copepods

Calanus oil is extracted from the copepods of the same name Calanus finmarchicus. ​According to Salma et al. (Prostaglandins Leukot Essent Fatty Acids​, 2016, Vol. 108, pp. 13-21), Calanus finmarchicus​ is “the most abundant crustacean in the North Atlantic Ocean with annual production of several hundred million tonnes.

“The total annual harvest amounts to less than 0.01% of the annual growth in accordance with regulations by Norwegian fisheries management.”

Calanus oil contains the omega-3s EPA and DHA predominantly in the wax ester form (the oil is slightly viscous). The oil also contains astaxanthin, which gives its ruby color.

Wax esters are historically associated with penguin, seal, and whale oil, but are being produced by Norwegian company Zooca (formerly Calanus AS) from C. finmarchicus. ​Zooca/ Calanus AS funded the new study.

Commenting on the new study, Jan Erik Olsen, Head of Sales and Marketing Human Health & Nutrition for Zooca, told us: “The main objective [of this collaborative study with The University in Hannover] is to define the best endpoints for future studies aimed towards health claims applications in different markets.

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