Clinical Trials & Research

Meanwhile, the Biden administration issued regulations to implement last year’s law to limit “surprise” medical bills to patients who get care outside their insurance networks. Health providers — doctors and hospitals — are already complaining that they will be asked to pick up too much of the bill to protect patients. This week’s panelists are

LcS and experimental animals LcS is present in Yakult 300 light yogurt beverage, which was purchased from Yakult Taiwan (Taipei, Taiwan). The LcS samples were created by freeze-drying 125 mL of Yakult 300 light beverage containing 1.25 × 1010 CFU to 11.88 g. The freeze-dried samples were adjusted to 2.44 g (2.5 × 109 CFU) in 1 mL distilled water, and the CFU of LcS

For years, Millicent McKinnon of Dallas went without health insurance. She was one of roughly 1 million Texans who earn too much to qualify for Medicaid in the state but too little to buy their own insurance. That is, until she died in 2019. She was 64 and had been unable to find consistent care

General characteristics of mice with PL-02 supplementation for four weeks As shown on Table 1, after four consecutive weeks of supplementation with PL-02, the weight of each group of mice showed stable growth; there was no significant difference between the groups, and there were no significant differences in the food intake and water intake of

NETZSCH-Gerätebau GmbH has recently published a new handook entitled “Thermal Analysis in the Pharmaceutical Field”. Image credit: Netzsch GmbH The book features more than 260 pages of content across eight chapters. The topics include methods (including DSC, TGA, STA and gas analysis); the proper characterization of amorphous and crystalline phases; ensuring purity, thermal stability and

It’s called a silent killer. Warnings are rare, but of the million people who suffer a ruptured brain aneurysm each year, almost half will die and only a third will recover without disabilities. A new study published in BMJ Open has measured for the first time a link between variations in size of the brain’s

1. WHO. Micronutrients. 2020. Available from: https://www.who.int/health-topics/micronutrients#tab=tab_1. Accessed May 2020. 2. Hong Nguyen P, Huybregts L, Sanghvi TG, Mai Tran L, Frongillo EA, Menon P, et al. Dietary Diversity Predicts the Adequacy of Micronutrient Intake in Pregnant Adolescent Girls and Women in Bangladesh, but Use of the 5-Group Cutoff Poorly Identifies Individuals with Inadequate Intake.

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded approximately $36.3 million to three academic institutions to conduct research to develop vaccines to protect against multiple types of coronaviruses and viral variants. The awards are intended to fuel vaccine research for a diverse family of coronaviruses,

RESEARCH HIGHLIGHT 27 September 2021 A pinch of salt for heart disease Replacing salt with a modified substitute has a beneficial impact on cardiovascular outcomes, according to a large, prospective trial. Karen O’Leary 0 Karen O’Leary Karen O’Leary is an Associate Research Analysis Editor with Nature Medicine. View author publications You can also search for

Colchicine is a commonly used drug to treat gout. It has been shown to produce an inhibitory effect on NLRP3 inflammasome. Inflammasomes play a role in inducing inflammation, and they are activated in coronavirus disease (COVID-19), with disease severity correlating with the extent of activation. Study: Colchicine for COVID-19 in adults in the community (PRINCIPLE):

A 2013 study by Pérez et al. reported a very high accumulation of the industrial chemical perfluorobutanoic acid (PFBA) in human lungs and kidneys. The German Federal Institute for Risk Assessment (BfR) checked these results using a more precise quantification method. The result: Only one sample contained a quantifiable PFBA value of 0.17 nanograms (ng)

Developing the advanced and powerful detection techniques to characterize as many endocrine disruptors as possible with ultra-sensitivity in the environment is still challenging, however highly demanded. Environmental estrogens (EEs), as typical endocrine disruptors, have been listed as one of the global environmental issues to be addressed through international collaboration by the United Nations. They are

1. Pearce EN, Lazarus JH, Moreno-Reyes R, Zimmermann MB. Consequences of iodine deficiency and excess in pregnant women: an overview of current knowns and unknowns. Am J Clin Nutr. 2016;104:918S–23S. CAS  PubMed  PubMed Central  Article  Google Scholar  2. Velasco I, Bath SC, Rayman MP. Iodine as essential nutrient during the first 1000 days of life.

A recent study published in the New England Journal of Medicine supports the efficacy of the mRNA-1273 vaccine in preventing coronavirus disease 2019 (COVID-19) illness and disease severity. At interim analysis in phase 3, randomized, observer-blind, and placebo-controlled clinical trial of the Moderna’s mRNA-1273 vaccine, the observations show that the vaccine remained safe and efficacious

Results from ICA In the results of ICA, outcomes of ICA model with five components generated the outcomes meet our expectation best. As to the first independent component (IC 1) (Fig. 1A), the histogram displayed that variables with high loading values were TG + PL 18:1n-9 and TG + PL 16:0, which are commonly with highest concentration in plasma. Additionally,

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has mutated since its initial emergence in Wuhan, China, in late 2019. to survive. A select few mutations have allowed the virus to spread faster and cause more severe infection. Variants of concern that contain such mutations, such as the Delta variant, have also acquired mutations to

Materials and chemicals Collagen peptides manufactured by Nitta Gelatin Inc. Osaka, Japan were used; higher molecular weight collagen peptides (HP): fish collagen peptides (average molecular weight 5000–7000 Da), lower molecular weight collagen peptides (LP): fish collagen peptides (average molecular weight < 1000 Da). Dipeptide content including Pro-Hyp and Hyp-Gly was about 0.1 g/kg in the HP and 3 g/kg in the

The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, China, in 2019. Subsequently, the global outbreak of the novel virus was announced to be a pandemic by the World Health Organization (WHO) in March 2020. The pandemic is popularly known as coronavirus disease 2019 (COVID-19). SARS-CoV-2 is extremely

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The onset of the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), led to an intensive and high-speed consolidation and further development of vaccine technology, leading to the rollout of vaccines against the virus throughout the developed world. Study: Comparative Effectiveness of Moderna, Pfizer-BioNTech, and Janssen (Johnson &

1. International Diabetes Federation. IDF Diabetes Atlas, 9th ed. Brussels, Belgium: International Diabetes Federation (IDF); 2019. 2. Janket SJ, Manson JE, Sesso H, Buring JE, Liu S. A prospective study of sugar intake and risk of type 2 diabetes in women. Diabetes Care. 2003;26:1008–15. Article  Google Scholar  3. Barclay AW, Flood VM, Rochtchina E, Mitchell

Coronavirus disease 2019 (COVID-19) has become one of the most concerning diseases globally since its initial outbreak. It is of great importance that monitoring new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants is ongoing because mutations could change viral biological properties. Viral genome alterations could alter neutralization efficiency resulting from naturally acquired immunity, and