Clinical Trials & Research

TORONTO and CHICAGO and WEDEL, Germany, Aug. 03, 2021 (GLOBE NEWSWIRE) — Medexus Pharmaceuticals Inc. (“Medexus” or the “Company”) (TSX: MDP) (OTCQX: MEDXF) and medac GmbH (“medac”) announced today that medac, Medexus’ licensor for treosulfan, has received a Complete Response Letter (CRL) from the Food and Drug Administration (FDA) in response to its New Drug

Scientists from Germany and Italy recently demonstrated the benefits of intramuscular/intranasal heterologous prime-boost vaccination regimen against coronavirus disease 2019 (COVID-19). They have shown that intranasal administration of adenovirus vector-based booster vaccine following prime immunization with a DNA- or mRNA-based vaccine induces robust mucosal and systemic antibody and T cell responses in mice. The study is

Experiments were conducted to establish a laser diffraction-based method for the determination of lactose powder particle size. This was accomplished using a Bettersizer 2600 equipped with a fully automatic dry dispersion system. This device enabled researchers to study the particle size measurement of lactose powders systematically. The impact of different dispersion pressures on the particle

INDIANAPOLIS, July 29, 2021 /PRNewswire/ – Today at the Alzheimer’s Association International Conference© (AAIC© 2021), Eli Lilly and Company (NYSE: LLY) presented two new exploratory analyses of data from the Phase 2 TRAILBLAZER-ALZ study. In the first, greater amyloid plaque changes following donanemab treatment was highly associated with less cognitive decline and participants with greater plaque clearance at 24 weeks

A US-based study has recently compared the viral load in vaccinated and unvaccinated individuals who have been infected with the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The findings reveal that vaccinated and unvaccinated individuals exhibit similar viral loads following delta infection and that vaccine breakthrough cases have the potential to transmit

International Gas Detectors’ TOCSIN 750S aspirated gas detector is an addressable aspirated gas detector that allows users to provide gas detection in areas that are otherwise harmful to normal diffusion sensors or difficult to approach. Image Credit: International Gas Detectors Ltd International Gas Detectors’ aspirated gas detectors are quiet in operation, have almost no moving

TARRYTOWN, N.Y., July 30, 2021 /PRNewswire/ – Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that the U.S. Food and Drug Administration (FDA) updated the Emergency Use Authorization (EUA) for the investigational COVID-19 antibody cocktail REGEN-COV™ (casirivimab and imdevimab). The authorization now includes post-exposure prophylaxis in people at high risk for progression to severe COVID-19, who are not fully vaccinated or are not

The London Ophthalmology Centre (LondonOC) has developed a new, non-invasive technique for the application of Xen stent into the eye to treat acute glaucoma. The micro device and new technique was successfully used to save the sight of former Children’s Laureate, Michael Rosen. Image Credit: London Ophthalmology Centre Mr Vik Sharma (MBBS BSc FRCOphth), Clinical

1. United Nations Children’s Fund (UNICEF), World Health Organization (WHO). UNICEF-WHO Low Birthweight Estimates: Levels and Trends 2000–2015. (World Health Organization, 2019). 2. Blencow, H. et al. National, regional, and worldwide estimates of low birthweight in 2015, with trends from 2000: A systematic analysis. Lancet Glob. Health 7(7), e849–e860. https://doi.org/10.1016/S2214-109X(18)30565-5 (2019). Article  Google Scholar  3.

The TOCSIN 635 gas detection control panel from International Gas Detectors (IGD) is perfectly suited for small- to medium-sized applications. It is a small format, cost-effective controller which is designed to support up to 1-8 or 1-32 detectors or devices. Image Credit: International Gas Detectors Ltd Utilizing a 2-core cable, the system includes IGD’s revolutionary

23 July 2021 Real-world data from Canada showed 82% and 87% effectiveness after one dose against hospitalisation or death caused by Beta/Gamma and Delta variants respectively  Results from the Canadian Immunization Research Network (CIRN) with support from Public Health Agency of Canada and the Canadian Institutes of Health Research, published as a pre-print, demonstrated one dose

Since the US Food and Drug Administration (FDA) established its accelerated approval pathway for drugs in 1992, nearly half (112) of the 253 drugs authorized have not been confirmed as clinically effective, an investigation by The BMJ has found. Elisabeth Mahase, clinical reporter at The BMJ, carried out an in depth analysis of FDA data

1. Herrero, M. et al. Greenhouse gas mitigation potentials in the livestock sector. Nat. Clim. Chang. 6, 452–461 (2016). ADS  Article  Google Scholar  2. Soussana, J. F. et al. Full accounting of the greenhouse gas (CO2, N2O, CH4) budget of nine European grassland sites. Agr. Ecosyst. Environ. 121, 121–134 (2007). CAS  Article  Google Scholar  3.

International Gas Detectors have created the revolutionary 750 safe area addressable gas detectors. All detectors are joined on a single two-core cable for the purpose of both communication and power by utilizing their advanced Sentinel+™ communication. Image Credit: International Gas Detectors Ltd The 750 safe area gas detectors from International Gas Detectors are provided with

News Clinical Trials Johnson & Johnson Statement on U.S. FDA Approval of Shelf Life Extension for Company’s COVID-19 Vaccine NEW BRUNSWICK, N.J., July 28, 2021 – We are pleased to confirm the U.S. Food & Drug Administration (FDA) has extended the shelf life for the Johnson & Johnson single-shot COVID-19 vaccine to six months. The decision

In late December 2019, a novel coronavirus was first reported in Wuhan, China, which showed high infectivity and caused pneumonia-like symptoms. Scientists later identified this RNA virus as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. Owing to rapid mutations, the continual emergence of several SARS-CoV-2 variants have been reported, among which some are

Materials and reagents WEC was prepared and supplied by Sun Chlorella (Kyoto, Japan). WEC contained ~10 μg/g PHA in dry matter　and 4.4 mg/g half cystine (information from supplier). PHA, proteinase inhibitor cocktail, butylated hydroxytoluene (BHA), phosphate-buffered saline (PBS, pH 7.4), diethylenetriamine pentaacetic acid (DTPA), 1,1,3,3-tetraethoxypropane (TEP), thiobarbituric acid (TBA), 2,3-diaminonaphthalene (DAN), enhanced chemiluminescence (ECL) reagent, acetonitrile (high-performance

SOUTH SAN FRANCISCO, Calif., July 28, 2021 (GLOBE NEWSWIRE) – Satsuma Pharmaceuticals, Inc. (Nasdaq: STSA), a clinical-stage biopharmaceutical company developing STS101 (dihydroergotamine (DHE) nasal powder), a novel investigational therapeutic product candidate for the acute treatment of migraine, today announced randomization of the first subject in its SUMMIT Phase 3 efficacy trial of STS101 for the acute

Johns Hopkins University scientists have developed a new tool for predicting which patients suffering from a complex inflammatory heart disease are at risk of sudden cardiac arrest. Published in Science Advances, their method is the first to combine models of patients’ hearts built from multiple images with the power of machine learning. “This robust new

1. Hatano S. Experience from a multicentre stroke register: a preliminary report. Bull World Health Organ. 1976;54:541–53. CAS  PubMed  PubMed Central  Google Scholar  2. Strong K, Mathers C, Bonita R. Preventing stroke: saving lives around the world. Lancet Neurol. 2007;6:182–7. https://doi.org/10.1016/S1474-4422(07)70031-5. Article  PubMed  Google Scholar  3. Kim BR, Lee J, Sohn MK, Kim DY, Lee

Cerba Research, previously Barc Lab, is extremely committed to delivering comprehensive central lab services. Image Credit: Cerba Research When working in partnership for global central laboratory services, Cerba Research’s industry-leading laboratories spanning five continents, and 35 years of experience, allow the company to focus on trial success. In 2016, Cerba Research collaborated with mid-level biotech

WILMINGTON, Del.–(BUSINESS WIRE) July 23, 2021 — Incyte Corporation (Nasdaq:INCY) today announced that the U.S. Food and Drug Administration (FDA) has issued a Complete Response Letter (CRL) regarding its Biologics License Application (BLA) for retifanlimab, an intravenous PD-1 inhibitor, for the treatment of adult patients with locally advanced or metastatic squamous cell carcinoma of the